Journal Guide

PLoS Biology features works of exceptional significance, originality, and relevance in all areas of biological science, from molecules to ecosystems, including works at the interface of other disciplines, such as chemistry, medicine, and mathematics. Our audience is the international scientific community as well as educators, policy makers, patient advocacy groups, and interested members of the public around the world.

PLoS Computational Biology features works of exceptional significance that further our understanding of living systems at all scales—from molecules and cells, to patient populations and ecosystems—through the application of computational methods. Readers include life and computational scientists, who can take the important findings presented here to the next level of discovery.Research articles that primarily describe new methods and offer only limited biological insight will be considered only in those exceptional instances in which the method is expected to significantly impact the field of computational biology, typically making substantial breakthroughs in areas of demonstrated importance. Research articles modeling aspects of biological systems should demonstrate both scientific novelty and profound new biological insights. Research articles describing improved or routine methods, models, software, and databases will not be considered by PLoS Computational Biology, and may be more appropriate for PLoS ONE.Generally, reliability and significance of biological discovery are validated and enriched by experimental studies. Experimental validation is not required for publication, however, nor does experimental validation of a modest biological discovery render a manuscript suitable for PLoS Computational Biology.For all submissions, authors must clearly provide detail, data, and software to ensure readers' ability to reproduce the models, methods, and results.Authors unsure of whether their work is within the scope of the journal should submit a presubmission inquiry.

Genetics and genomics research has grown at a bewildering pace in the past 15 years. The techniques of these fields are being applied to a wealth of biological questions and experimental systems. PLoS Genetics reflects the full breadth and interdisciplinary nature of this research by publishing outstanding original contributions in all areas of biology.PLoS Genetics publishes human studies, as well as research on model organisms—from mice and flies, to plants and bacteria. Our emphasis is on studies of broad interest that provide significant mechanistic insight into a biological process or processes. Topics include (but are not limited to) gene discovery and function, population genetics, genome projects, comparative and functional genomics, medical genetics, disease biology, evolution, gene expression, complex traits, chromosome biology, and epigenetics.Please refer to our Author Guidelines and Frequently Asked Questions when you are preparing manuscripts for submission. If you are unsure whether your work is suitable for PLoS Genetics, you can send a Presubmission Inquiry.

PLOS ONE welcomes original research submissions from the natural sciences, medical research, engineering, as well as the related social sciences and humanities, including:

• Primary research that contributes to the base of scientific knowledge, including interdisciplinary, replication studies, and negative or null results.

• Systematic reviews whose methods ensure the comprehensive and unbiased sampling of existing literature.

• Submissions describing methods, software, databases, or other tools that meet the journal’s criteria for utility, validation and availability.

• Qualitative research that adheres to appropriate study design and reporting guidelines.

• Protocols, including Lab Protocols that describe verified methodologies and Study Protocols that describe detailed plans for research projects.

Bacteria, fungi, parasites, prions and viruses cause a plethora of diseases that have important medical, agricultural, and economic consequences. Moreover, the study of microbes continues to provide novel insights into such fundamental processes as the molecular basis of cellular and organismal function. PLoS Pathogens reflects the full breadth of research in these areas by publishing outstanding original articles that significantly advance the understanding of pathogens and how they interact with their host organisms. Topics include (but are not limited to) adaptive and innate immune defenses as well as pathogen countermeasures, emerging pathogens, evolution, genomics and gene regulation, model host organisms, pathogen-cell biology, pathogenesis, prions, proteomics and signal transduction, rational vaccine design, structural biology, and virulence factors.PLoS Pathogens will consider studies that provide fundamental new understanding of the pathogen or pathogenic mechanisms. The journal will not consider purely descriptive studies, such as those that solely identify a new genomic sequence of a related pathogen or a series of related pathogens, the isolation of pathogen variants, or a new strain or type based only on sequence analysis. Such studies, as well as correlative studies of host and pathogen genotypes, would be considered if they use further experiments to test an idea or validate a mechanistic model, or to provide a clear set of novel conclusions that derive from the data.

Pancreas provides a central forum for communication of original works involving both basic and clinical research on the exocrine and endocrine pancreas and their interrelationships and consequences in disease states. This multidisciplinary, international journal covers the whole spectrum of basic sciences, etiology, prevention, pathophysiology, diagnosis, and surgical and medical management of pancreatic diseases, including cancer. Website: www.pancreasjournal.com.

Pancreatology is the official journal of the International Association of Pancreatology (IAP), the European Pancreatic Club (EPC) and several national societies and study groups around the world. Dedicated to the understanding and treatment of exocrine as well as endocrine pancreatic disease, this multidisciplinary periodical publishes original basic, translational and clinical pancreatic research from a range of fields including gastroenterology, oncology, surgery, pharmacology, cellular and molecular biology as well as endocrinology, immunology and epidemiology. Readers can expect to gain new insights into pancreatic physiology and into the pathogenesis, diagnosis, therapeutic approaches and prognosis of pancreatic diseases. The journal features original articles, case reports, consensus guidelines and topical, cutting edge reviews, thus representing a source of valuable, novel information for clinical and basic researchers alike.

''Pathobiology'' offers a valuable platform for the publication of high-quality original research into the mechanisms underlying human disease. Aiming to serve as a bridge between basic biomedical research and clinical medicine, the journal welcomes articles from scientific areas such as pathology, oncology, anatomy, virology, internal medicine, surgery, cell and molecular biology, and immunology. Published bimonthly, ''Pathobiology'' features original research papers and reviews on translational research. The journal offers the possibility to publish proceedings of meetings dedicated to one particular topic.

Pathogens (ISSN 2076-0817) publishes reviews, regular research papers and short notes on all aspects of pathogens and pathogen-host interactions. There is no restriction on the length of the papers. Our aim is to encourage scientists to publish their experimental and theoretical research in as much detail as possible. Full experimental and/or methodical details must be provided for research articles. There are, in addition, unique features of this journal: manuscripts regarding research proposals and research ideas will be particularly welcomed computed data or files regarding the full details of the experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material

Pathology & Oncology Research (POR) is an interdisciplinary journal at the interface of pathology and oncology, including the preclinical and translational research, diagnostics and therapy. Furthermore, POR offers an international forum for the rapid communication of reviews, original research, critical and topical reports with excellence and novelty. Published quarterly, POR is dedicated to keeping scientists informed of developments in its focused biomedical fields which span the gap between basic research and clinical medicine. A special aim of POR is to promote publishing activity in pathology and oncology of colleagues in the Central and East European region. The journal will interest pathologists, and a broad range of experimental and clinical oncologists, and related experts. Pathology & Oncology Research is supported by distinguished international advisory board and the Arányi Foundation for modern pathology.

Pathology, Research and Practice provides accessible coverage of the most recent developments across the entire field of pathology: Reviews focus on recent progress in pathology, while Comments look at interesting current problems and at hypotheses for future developments in pathology. Original Papers present novel findings on all aspects of general, anatomic and molecular pathology. Rapid Communications inform readers on preliminary findings that may be relevant for further studies and need to be communicated quickly. Teaching Cases look at new aspects or special diagnostic problems of diseases and at case reports relevant for the pathologist's practice.

Neil Armstrong, University of Exeter, UKTom Baranowski, University of TexasGaston P. Beunen, K.U. Leuven, BelgiumCameron Blimkie, McMaster University, CanadaColin Boreham, University College Dublin, IrelandCharles B. Corbin, Arizona State UniversityRoger Eston, University of Exeter, UKAvery Faigenbaum, The College of New JerseyBareket Falk, Brock University, CanadaPatty Freedson, University of MassachusettsJoseph Hamill, University of MassachusettsAnthony Mahon, Ball State UniversityRobert M. Malina, Tarleton State UniversityStephen Paridon, Children’s Hospital of PhiladelphiaRussell Pate, University of South CarolinaJames Pivarnik, Michigan State UniversityChris Riddoch, University of Bath, UKJames Sallis, University of California-San DiegoRoy Shephard, University of Toronto, CanadaEmmanuel Van Praagh, Universite Blaise Pascal, FranceMaureen R. Weiss, University of Minnesota.

biomedical, health, genetics, ecology, biology

Peptides is an international journal presenting original contributions on the chemistry, biochemistry, neurochemistry, endocrinology, gastroenterology, physiology, and pharmacology of peptides, as well as their neurological, psychological and behavioral effects. Peptides emphasizes all aspects of peptide research and covers investigations of these proteins in plants, insects, lower vertebrates, animals and clinical studies in humans.Please bookmark this URL: http://www.elsevier.com/locate/peptidesUS National Institutes of Health (NIH) voluntary posting ("Public Access") policy:Peptides and Elsevier facilitate the author's response to the NIH Public Access Policy. For more details please see the Guide for authors.Benefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services .Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our support pages: http://support.elsevier.com

Personalized Medicine is a peer-reviewed journal presenting reviews and reports by scientists and decision-makers most closely involved in this rapidly developing area. Personalized Medicine aims at being an essential resource for keeping abreast of the latest developments in all areas of this exciting new field, and focuses on those aspects of most direct relevance to the pharmaceutical industry and wider clinical community.

Pesticide Biochemistry and Physiology publishes original scientific articles pertaining to the mode of action of plant protection agents such as insecticides, fungicides, herbicides, and similar compounds, including nonlethal pest control agents, biosynthesis of pheromones, hormones, and plant resistance agents. Manuscripts may include a biochemical, physiological, or molecular study for an understanding of comparative toxicology or selective toxicity of both target and nontarget organisms. Particular interest will be given to studies on the molecular biology of pest control, toxicology, and pesticide resistance.Research Areas Emphasized Include the Biochemistry and Physiology of:• Comparative toxicity• Mode of action• Pathophysiology• Plant growth regulators• Resistance• Other effects of pesticides on both parasites and hostsBenefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services .Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our support pages: http://support.elsevier.com