Journal Guide

Microvascular Research is dedicated to the dissemination of fundamental information related to the microvascular field. Full-length articles presenting the results of original research and brief communications are featured.Research Areas include:• Angiogenesis• Biochemistry• Bioengineering• Biomathematics• Biophysics• Cancer• Circulatory homeostasis• Comparative physiology• Drug delivery• Neuropharmacology• Pathology• RheologyMicrovascular Research's Most downloaded articles on ScienceDirectUS National Institutes of Health (NIH) voluntary posting ("Public Access") policyMicrovascular Research and Elsevier facilitate the author's response to the NIH Public Access Policy. For more details please see the Guide for authors

Aims: Molbank is a communication journal of synthetic chemistry and natural product chemistry. It publishes short notes of experimental data records for individual molecules (one compound per paper). Any scattered unassembled experimental data for individual compounds which is conventionally not publishable is particularly welcome. Availability of compound samples is published and considered as important information. Authors are encouraged to register or deposit their chemical samples through the non-profit international organization Molecular Diversity Preservation International (MDPI). Molbank has been launched to preserve and exploit molecular diversity of both chemical information and chemical substances. Scope: organic synthesis, biosynthesis, natural product isolation and derivatization, structural elucidation (X-ray crystallography, NMR, etc.)

The accelerating determination of genome sequences and their interpretation (genomics) has brought with it one of the most daunting challenges to modern bioscience--the concomitant determination of the structure, function, and expression of the corresponding proteins encoded therein. The magnitude of this task is staggering. The difficulties arise at many stages, ranging from protein isolation and identification to structure determination, protein/protein interactions and gene expression, and the answers will require both existing technologies and methods yet to be developed. Thus, this rapidly expanding field of proteomics, a term coined in evident parallel to genomics, is both an extension of traditional biochemistry and at the same time a new and exciting field. Moreover, the magnitude of this effort will produce volumes of data that will dwarf previous outputs and pose severe problems in their own right. The storage, analysis and manipulation of this information, a problem already realized from genomic studies, has spawned a related field generally called bioinformatics. It is likely that these data sets will drive discovery and research that is unparalleled in the history of bioscience and could eclipse, at least in the early stages, hypothesis-driven experimentation. The management of research databases is not a new phenomenon, but the size of the task will require new and innovative approaches.

It is the primary objective of this publication to encourage the bridging of the gap between clinicians of all relevant specialities and biomedical scientists working in areas from biochemistry and molecular and cell biology to physiology, pharmacology and pathology. A spectrum of topics in medicine will be selected to illustrate not only the molecular insights that derive from the application of basic science, but also the variety of challenging problems that medicine is able to offer the basic scientist. The Editors and publisher anticipate that most of the authors contributing to the series will be practising clinical scientists who will develop their own personal perspective as an extended review on the molecular aspects of a field of medicine in which they are working, addressing themselves both to the doctor who is ill-at-ease with basic science, and to the basic scientist with little awareness of the problems of clinical practice.Benefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services .Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our support pages: http://support.elsevier.com

Molecular Biotechnology publishes original research papers on the application of molecular biology to both basic and applied research in biotechnology. Particular areas of interest include the stability and expression of cloned gene products, cell transformation, gene cloning systems and the production of recombinant proteins, protein purification and analysis, transgenic species, developmental biology, mutation analysis, the applications of DNA fingerprinting, RNA interference, and PCR technology, microarray technology, proteomics, mass spectrometry, bioinformatics, plant molecular biology, microbial genetics, gene probes and the diagnosis of disease, pharmaceuticals, therapeutic agents, vaccines, gene targeting, gene therapy, stem cell technology and tissue engineering, antisense technology, protein engineering and enzyme technology, monoclonal antibodies, glycobiology and glycomics, and agricultural biotechnology. The journal also presents review articles on subjects in these areas.

Molecular Cytogenetics encompasses all aspects of chromosome biology and the application of molecular cytogenetic techniques in all areas of biomedicine.

Molecular Genetics and Metabolism is a contribution to the understanding of the metabolic basis of disease. The journal publishes articles describing investigations that use the tools of biochemistry and molecular biology for studies of normal and diseased states. In addition to original research articles, occasional minireviews reporting timely advances as well as brief communications and letters to the editor are considered.Research Areas include:• Inherited Metabolic Diseases:- Biochemical studies of primary enzyme defects- Molecular genetic analyses of mutations- Pathogenesis of these disorders, including not only primary but also secondary metabolic alterations• Systems Biology:- Functional integration of biochemical network modules- Moonlighting functions of proteins• Intercellular and Intracellular Metabolic Relationships:- Biochemical interactions between cells- Functional roles of and interactions between subcellular compartments and distinct regions within these cellular spaces, termed microcompartments- Metabolic relations between individual enzymes and pathways• Cellular Catalysts:- Protein and nonprotein catalyst in normal and deranged cellular metabolism- Relationships between the structure and function of catalytic molecules- Interaction of these catalysts with other cellular components• Disease Pathogenesis:- Underlying mechanisms of inherited and acquired diseases- Relationships between genotype and phenotype at the biochemical and molecular levels• Treatment:- Drug, protein and dietary interventions- Transplantation and gene therapy- Multicenter clinical trialsAdvances in nanomedicine, nanopediatrics and nanotechnology are also welcome.

* Biological Abstracts® (Thomson ISI) * BIOSIS Previews® (Thomson ISI) * Chemical Abstracts Service (CAS) * EMBASE (Elsevier) * Google Scholar * Index Copernicus (IC) * Index Medicus/MEDLINE/PubMed (NLM) * Journal Citation Reports (JCR) Science Edition (Thomson ISI) * Science Citation Index Expanded® (Thomson ISI) * Scopus (Elsevier).

Molecular engineering employs experimental, theoretical and computational approaches to establish new understanding of molecular properties and behaviours and uses this understanding to design and assemble better materials, systems, and processes to achieve specific functions. MSDE provides a hub for research into new understanding of molecular systems and the use of this understanding in applications of technological significance that help address global challenges.

Molecular and Cellular Endocrinology was established in 1974 to meet the demand for integrated publication on all aspects related to the biochemical effects, synthesis and secretions of extracellular signals (hormones, neurotransmitters, etc.) and to the understanding of cellular regulatory mechanisms involved in hormonal control.The journal is fulfilling this aim by publishing full-length original research papers, rapid papers, invited reviews, At the Cutting Edge essays, and book reviews.The scope encompasses all subjects related to biochemical and molecular aspects of endocrine research and cell regulation. These include: (1) mechanisms of action of extracellular signals (hormones, neurotransmitters, etc.), (2) interaction of these factors with receptors, (3) generation, action and role of intracellular signals such as cyclic nucleotides and calcium, (4) hormone-regulated gene expression, (5) structure and physicochemical properties of hormones, hormone receptors and other hormone-binding components, (6) synthesis, secretion, metabolism and inactivation of hormones, neurotransmitters, etc. (7) hormonal control of differentiation, (8) related control mechanisms in non-mammalian systems, (9) methodological and theoretical aspects related to hormonal control processes, (10) clinical studies as far as they throw new light on basic research in this field, (11) control of intermediary metabolism at the cellular level, (12) ultrastructural aspects related to hormone secretion and action.Please bookmark this URL: http://www.elsevier.com/locate/mceUS National Institutes of Health (NIH) voluntary posting ("Public Access") policyMolecular and Cellular Endocrinology and Elsevier facilitate the author's response to the NIH Public Access Policy. For more details please see the Guide for authors

The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds.The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal.Natural Product Research issues will be subtitled either "Part A - Synthesis and Structure" or "Part B - Bioactive Natural Products". for details on this , see the forthcoming articles section.All published research articles in Natural Product Research have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by expert referees.DisclaimerTaylor & Francis makes every effort to ensure the accuracy of all the information (the "Content") contained in its publications. However, Taylor & Francis and its agents and licensors make no representations or warranties whatsoever as to the accuracy, completeness or suitability for any purpose of the Content and disclaim all such representations and warranties whether express or implied to the maximum extent permitted by law. Any views expressed in this publication are the views of the authors and are not the views of Taylor & Francis.

Nature Methods is a forum for the publication of novel methods and significant improvements to tried-and-tested basic research techniques in the life sciences. This monthly publication is aimed at a broad, interdisciplinary audience of academic and industry researchers actively involved in laboratory practice. It provides them with new tools to conduct their research and places a strong emphasis on the immediate practical relevance of the work presented.The journal publishes primary research papers as well as overviews of recent technical and methodological developments. We are actively seeking primary methods papers of relevance to the biological and biomedical sciences, including methods grounded in chemistry that have a practical application to the study of biological problems.To enhance the practical relevance of each paper, description of the method must be accompanied by its validation, its application to an important biological question and results illustrating its performance in comparison to available approaches. Articles are selected for publication that present broad interest, thorough assessments of methodological performance and comprehensive technical descriptions that facilitate immediate application.Specific areas of interest include, but are not limited to:* Methods for nucleic acid manipulation, amplification and sequencing* Methods for protein engineering, expression and purification* Methods for proteomics, including mass spectrometry, analysis of binding interactions, microarray-based technologies, display techniques, analysis of post-translational modifications, glycobiology and metabolomics* Methods for systems biology, including proteomics approaches, protein interaction analysis methods and genome wide expression and regulation profiling* Biomolecular structural analysis technologies, including NMR and crystallography* Chemical biology techniques, including chemical labeling, methods for expanding the genetic code and directed evolution* Biophysical methods, including single molecule and lab-on-a-chip technologies* Optical and non-optical imaging technologies, including probe design and labeling methods, microscopy, spectroscopy and in vivo imaging* Techniques for the analysis and manipulation of gene expression, including epigenetics, gene targeting, transduction, RNA interference and microarray-based technologies* Methods for cell culture and manipulation, including stem cells, single cell methods and lab-on-a-chip technologies* Immunological techniques, including production of antibodies, antibody-based assays and immunolabeling* Methods for the study of physiology and disease processes including cancer* Methods involving model organisms and their manipulation and phenotyping* Computational and bioinformatic methods for analysis, modeling or visualization of biological data* Nanotechnology-based methods applied to basic biology.

Basic, translational and clinical research on the following topics as they relate to stress will be covered:

• Molecular substrates and cell signaling
• Genetics and epigenetics
• Stress circuitry
• Structural and physiological plasticity
• Developmental Aspects
• Laboratory models of stress
• Neuroinflammation and pathology
• Memory and Cognition
• Motivational Processes
• Fear and Anxiety
• Stress-related neuropsychiatric disorders (including depression, PTSD, substance abuse)
• Neuropsychopharmacology

The journal provides a source for communication on the latest findings in all areas of contemporary neurochemistry and other fields of relevance (including molecular biology, biochemistry, physiology, neuroimmunology, pharmacology) in order to expand understanding of the functions of nervous system. It presents papers on functional neurochemistry, nervous system receptors, neurotransmitters, myelin, chromaffin granules and other components of the nervous system, as well as neurophysiological and clinical aspects, behavioral reactions, etc. Relevant topics include structure and function of the nervous system proteins, neuropeptides, nucleic acids, nucleotides, lipids, and other biologically active components. The journal presents theoretical material suggesting novel principles and approaches to neurochemical problems, presentations of new hypotheses and significant findings, discussions, chronicles of congresses, meetings, and conferences with short presentations of the most sensational and timely reports, in

Neurochemical Research is devoted to the rapid publication of studies that use neurochemical methodology in research on nervous system structure and function. The journal publishes original reports of experimental and clinical research results, perceptive reviews of significant problem areas in the neurosciences, brief comments of a methodological or interpretive nature, and research summaries conducted by leading scientists whose works are not readily available in English.

NJC (New Journal of Chemistry) is a broad-based primary journal encompassing all branches of chemistry and its sub-disciplines. It publishes high-quality work that opens new directions in chemistry or in other scientific disciplines. Research must demonstrate that it will have an impact on areas of research other than that of the reported work.

Nitric Oxide: Biology and Chemistry includes original research, methodology papers and reviews relating to nitric oxide and other gasotransmitters such as hydrogen sulfide and carbon monoxide. Special emphasis is placed on the biological chemistry, physiology, pharmacology, enzymology and pathological significance of these molecules in human health and disease. The journal also accepts manuscripts relating to plant and microbial studies involving these molecules.Benefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services.Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our support pages: http://support.elsevier.com

microRNA, small interfering RNA, RNAi, lincRNA, piRNA, silencing